<\/a><\/p>\n\u039f\u03b9 \u03c0\u03c1\u03bf\u03c4\u03b5\u03b9\u03bd\u03cc\u03bc\u03b5\u03bd\u03b5\u03c2 \u03b7\u03bc\u03b5\u03c1\u03ae\u03c3\u03b9\u03b5\u03c2 \u03b4\u03cc\u03c3\u03b5\u03b9\u03c2 \u03c0\u03c1\u03cc\u03c3\u03bb\u03b7\u03c8\u03b7\u03c2 \u03b3\u03b9\u03b1 \u03c4\u03bf Se \u03b5\u03af\u03bd\u03b1\u03b9 55-75 \u03bcg\/\u03b7\u03bc. \u0395\u03c0\u03b5\u03b9\u03b4\u03ae \u03b3\u03b5\u03bd\u03b9\u03ba\u03ac \u03c4\u03b1 \u03c6\u03c5\u03c4\u03ac \u03c4\u03b7\u03c2 \u0395\u03c5\u03c1\u03ce\u03c0\u03b7\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c0\u03c4\u03c9\u03c7\u03ac \u03c3\u03b5 Se, \u03ad\u03bd\u03b1 \u03bc\u03b5\u03b3\u03ac\u03bb\u03bf \u03bc\u03ad\u03c1\u03bf\u03c2 \u03c4\u03bf\u03c5 \u03c0\u03bb\u03b7\u03b8\u03c5\u03c3\u03bc\u03bf\u03cd \u03ad\u03c7\u03b5\u03b9 \u03c7\u03b1\u03bc\u03b7\u03bb\u03ac \u03b5\u03c0\u03af\u03c0\u03b5\u03b4\u03b1 Se \u03c3\u03c4\u03bf \u03b1\u03af\u03bc\u03b1 \u03bc\u03b5 \u03cc\u03c4\u03b9 \u03b1\u03c5\u03c4\u03cc \u03c3\u03c5\u03bd\u03b5\u03c0\u03ac\u03b3\u03b5\u03c4\u03b1\u03b9 \u03c3\u03b5 \u03b1\u03c1\u03ba\u03b5\u03c4\u03ad\u03c2 \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b5\u03c2 \u03c4\u03bf\u03c5 \u03bf\u03c1\u03b3\u03b1\u03bd\u03b9\u03c3\u03bc\u03bf\u03cd.
\n\u0393\u03b5\u03bd\u03b9\u03ba\u03ac \u03b7 \u03c0\u03c1\u03cc\u03c3\u03bb\u03b7\u03c8\u03b7 Se \u03bc\u03b5 \u03c4\u03b9\u03c2 \u03c4\u03c1\u03bf\u03c6\u03ad\u03c2 \u03c0\u03bf\u03b9\u03ba\u03af\u03bb\u03b5\u03b9 \u03b1\u03c0\u03cc 7-4990 \u03bcg \u03b7\u03bc\u03b5\u03c1\u03b7\u03c3\u03af\u03c9\u03c2, \u03bc\u03b5 \u03bc\u03ad\u03c3\u03b5\u03c2 \u03c4\u03b9\u03bc\u03ad\u03c2 \u03b3\u03b9\u03b1 \u03c4\u03b7\u03bd \u0395\u03c5\u03c1\u03ce\u03c0\u03b7 40 \u03bcg\/\u03b7\u03bc\u03b5\u03c1., \u03b5\u03bd\u03ce \u03b3\u03b9\u03b1 \u03c4\u03b9\u03c2 \u0397\u03a0\u0391 \u03bf\u03b9 \u03bc\u03ad\u03c3\u03b5\u03c2 \u03c4\u03b9\u03bc\u03ad\u03c2 \u03b3\u03b9\u03b1 \u03c4\u03b9\u03c2 \u03b3\u03c5\u03bd\u03b1\u03af\u03ba\u03b5\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 93 \u03bcg\/\u03b7\u03bc\u03b5\u03c1 \u03ba\u03b1\u03b9 \u03b3\u03b9\u03b1 \u03c4\u03bf\u03c5\u03c2 \u03ac\u03bd\u03c4\u03c1\u03b5\u03c2 134 \u03bcg \u03b7\u03bc\u03b5\u03c1\u03b7\u03c3\u03af\u03c9\u03c2. \u0397 \u039a\u03af\u03bd\u03b1 \u03ad\u03c7\u03b5\u03b9 \u03c0\u03b5\u03c1\u03b9\u03bf\u03c7\u03ad\u03c2 \u03c0\u03bf\u03c5 \u03c7\u03b1\u03c1\u03b1\u03ba\u03c4\u03b7\u03c1\u03af\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03ad\u03bb\u03bb\u03b5\u03b9\u03c8\u03b7 Se, \u03cc\u03c0\u03c9\u03c2 \u03b5\u03c0\u03af\u03c3\u03b7\u03c2 \u03ba\u03b1\u03b9 \u03c0\u03b5\u03c1\u03b9\u03bf\u03c7\u03ad\u03c2 \u03bc\u03b5 \u03c5\u03c8\u03b7\u03bb\u03ad\u03c2 \u03c0\u03b5\u03c1\u03b9\u03b5\u03ba\u03c4\u03b9\u03ba\u03cc\u03c4\u03b7\u03c4\u03b5\u03c2 \u03c4\u03bf\u03c5 \u03b9\u03c7\u03bd\u03bf\u03c3\u03c4\u03bf\u03b9\u03c7\u03b5\u03af\u03bf\u03c5 (4,5).
\n\u03a4\u03bf Se \u03c3\u03c5\u03bc\u03bc\u03b5\u03c4\u03ad\u03c7\u03b5\u03b9 \u03c3\u03b5 \u03b1\u03c1\u03ba\u03b5\u03c4\u03ad\u03c2 \u03b2\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ad\u03c2 \u03b4\u03c1\u03ac\u03c3\u03b5\u03b9\u03c2 \u03cc\u03c0\u03c9\u03c2 \u03c3\u03c4\u03bf\u03bd \u03ba\u03b1\u03c4\u03b1\u03b2\u03bf\u03bb\u03b9\u03c3\u03bc\u03cc \u03c4\u03c9\u03bd \u03b5\u03bb\u03b5\u03c5\u03b8\u03ad\u03c1\u03c9\u03bd \u03c1\u03b9\u03b6\u03ce\u03bd, \u03c3\u03c4\u03b7\u03bd \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b1 \u03c4\u03bf\u03c5 \u03b1\u03bd\u03bf\u03c3\u03bf\u03c0\u03bf\u03b9\u03b7\u03c4\u03b9\u03ba\u03bf\u03cd \u03c3\u03c5\u03c3\u03c4\u03ae\u03bc\u03b1\u03c4\u03bf\u03c2, \u03c3\u03b5 \u03b4\u03b9\u03ac\u03c6\u03bf\u03c1\u03b5\u03c2 \u03b5\u03bd\u03b4\u03bf\u03ba\u03c1\u03b9\u03bd\u03b9\u03ba\u03ad\u03c2 \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b5\u03c2 \u03cc\u03c0\u03c9\u03c2 \u03b5\u03c0\u03af\u03c3\u03b7\u03c2 \u03ba\u03b1\u03b9 \u03c3\u03c4\u03b7\u03bd \u03c0\u03c1\u03cc\u03bb\u03b7\u03c8\u03b7 \u03c4\u03b7\u03c2 \u03ba\u03b1\u03c1\u03ba\u03b9\u03bd\u03bf\u03b3\u03ad\u03bd\u03b5\u03c3\u03b7\u03c2. \u0394\u03c1\u03b1 \u03b4\u03b7\u03bb\u03b1\u03b4\u03ae \u03c3\u03b1\u03bd \u03ad\u03bd\u03b1 \u03c0\u03bf\u03bb\u03cd \u03ba\u03b1\u03bb\u03cc \u03b1\u03bd\u03c4\u03b9\u03bf\u03be\u03b5\u03b9\u03b4\u03c9\u03c4\u03b9\u03ba\u03cc. \u03a3\u03c4\u03b9\u03c2 \u03c0\u03b5\u03c1\u03b9\u03c3\u03c3\u03cc\u03c4\u03b5\u03c1\u03b5\u03c2 \u03b1\u03c0\u03cc \u03b1\u03c5\u03c4\u03ad\u03c2 \u03c4\u03b9\u03c2 \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b5\u03c2 \u03b4\u03b9\u03b1\u03bc\u03b5\u03c3\u03bf\u03bb\u03b1\u03b2\u03bf\u03cd\u03bd 30 \u03c4\u03bf\u03c5\u03bb\u03ac\u03c7\u03b9\u03c3\u03c4\u03bf\u03bd \u03c3\u03b5\u03bb\u03b7\u03bd\u03bf\u03c0\u03c1\u03c9\u03c4\u03b5\u03ca\u03bd\u03b5\u03c2, \u03bf\u03b9 \u03bf\u03c0\u03bf\u03af\u03b5\u03c2 \u03c3\u03c4\u03bf\u03bd \u03ac\u03bd\u03b8\u03c1\u03c9\u03c0\u03bf \u03b5\u03ba\u03c6\u03c1\u03ac\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc 25 \u03c4\u03bf\u03c5\u03bb\u03ac\u03c7\u03b9\u03c3\u03c4\u03bf\u03bd \u03b3\u03bf\u03bd\u03af\u03b4\u03b9\u03b1 (6).<\/p>\n
\u039f \u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03ae\u03c2 \u03c0\u03b5\u03c1\u03b9\u03ad\u03c7\u03b5\u03b9 \u03c0\u03b5\u03c1\u03b9\u03c3\u03c3\u03cc\u03c4\u03b5\u03c1\u03bf Se, \u03b1\u03bd\u03ac \u03b3\u03c1\u03b1\u03bc\u03bc\u03ac\u03c1\u03b9\u03bf \u03b9\u03c3\u03c4\u03bf\u03cd, \u03c3\u03b5 \u03c3\u03c7\u03ad\u03c3\u03b7 \u03bc\u03b5 \u03bf\u03c0\u03bf\u03b9\u03bf\u03b4\u03ae\u03c0\u03bf\u03c4\u03b5 \u03ac\u03bb\u03bb\u03bf \u03cc\u03c1\u03b3\u03b1\u03bd\u03bf \u03c4\u03bf\u03c5 \u03c3\u03ce\u03bc\u03b1\u03c4\u03bf\u03c2. \u03a4\u03bf Se, \u03cc\u03c0\u03c9\u03c2 \u03c4\u03bf \u03b9\u03ce\u03b4\u03b9\u03bf \u03ba\u03b1\u03b9 \u03bf \u03c3\u03af\u03b4\u03b7\u03c1\u03bf\u03c2, \u03b5\u03af\u03bd\u03b1\u03b9 \u03ad\u03bd\u03b1 \u03b2\u03b1\u03c3\u03b9\u03ba\u03cc \u03b9\u03c7\u03bd\u03bf\u03c3\u03c4\u03bf\u03b9\u03c7\u03b5\u03af\u03bf \u03b3\u03b9\u03b1 \u03c4\u03b7\u03bd \u03c6\u03c5\u03c3\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ae \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b1 \u03c4\u03bf\u03c5 \u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03ae, \u03cc\u03c0\u03c9\u03c2 \u03b5\u03c0\u03af\u03c3\u03b7\u03c2 \u03b3\u03b9\u03b1 \u03c4\u03b7\u03bd \u03bf\u03bc\u03bf\u03b9\u03cc\u03c3\u03c4\u03b1\u03c3\u03b7 \u03c4\u03c9\u03bd \u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03b9\u03ba\u03ce\u03bd \u03bf\u03c1\u03bc\u03bf\u03bd\u03ce\u03bd.
\n\u0388\u03c7\u03bf\u03c5\u03bd \u03b1\u03bd\u03b1\u03c6\u03b5\u03c1\u03b8\u03b5\u03af \u03b5\u03c5\u03b5\u03c1\u03b3\u03b5\u03c4\u03b9\u03ba\u03ac \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03ad\u03c3\u03bc\u03b1\u03c4\u03b1 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03c7\u03bf\u03c1\u03ae\u03b3\u03b7\u03c3\u03b7 Se \u03c3\u03b5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03c0\u03bf\u03c5 \u03c0\u03ac\u03c3\u03c7\u03bf\u03c5\u03bd \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03bd\u03cc\u03c3\u03bf Hashimoto (\u039dH). \u03a3\u03c5\u03b3\u03ba\u03b5\u03ba\u03c1\u03b9\u03bc\u03ad\u03bd\u03b1, \u03b1\u03c0\u03cc 11 \u03c0\u03b5\u03c1\u03af\u03c0\u03bf\u03c5 \u03b5\u03c1\u03b3\u03b1\u03c3\u03af\u03b5\u03c2 \u03c0\u03bf\u03c5 \u03b1\u03c6\u03bf\u03c1\u03bf\u03cd\u03c3\u03b1\u03bd \u03c4\u03b7\u03bd \u03c7\u03bf\u03c1\u03ae\u03b3\u03b7\u03c3\u03b7 Se \u03c3\u03b5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 NH, 7 \u03ad\u03b4\u03b5\u03b9\u03be\u03b1\u03bd \u03b2\u03b5\u03bb\u03c4\u03af\u03c9\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03c4\u03af\u03c4\u03bb\u03bf\u03c5 \u03c4\u03c9\u03bd TPO \u03b1\u03bd\u03c4\u03b9\u03c3\u03c9\u03bc\u03ac\u03c4\u03c9\u03bd (\u03c7\u03b1\u03c1\u03b1\u03ba\u03c4\u03b7\u03c1\u03b9\u03c3\u03c4\u03b9\u03ba\u03cc \u03b3\u03bd\u03ce\u03c1\u03b9\u03c3\u03bc\u03b1 \u03c4\u03b7\u03c2 NH), \u03c0\u03c1\u03ac\u03b3\u03bc\u03b1 \u03c0\u03bf\u03c5 \u03ba\u03b1\u03c4\u03b1\u03b4\u03b5\u03b9\u03ba\u03bd\u03cd\u03b5\u03b9 \u03cc\u03c4\u03b9 \u03c4\u03b1 \u03c5\u03c8\u03b7\u03bb\u03ac \u03b5\u03c0\u03af\u03c0\u03b5\u03b4\u03b1 Se \u03c3\u03c4\u03bf \u03b1\u03af\u03bc\u03b1 \u03c3\u03c5\u03c3\u03c7\u03b5\u03c4\u03af\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03c7\u03b1\u03bc\u03b7\u03bb\u03ac \u03b5\u03c0\u03af\u03c0\u03b5\u03b4\u03b1 TPO \u03b1\u03bd\u03c4\u03b9\u03c3\u03c9\u03bc\u03ac\u03c4\u03c9\u03bd.
\n\u0398\u03b1 \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03b5\u03b4\u03ce \u03bd\u03b1 \u03b5\u03c0\u03b9\u03c3\u03b7\u03bc\u03ac\u03bd\u03bf\u03c5\u03bc\u03b5 \u03cc\u03c4\u03b9 \u03b7 \u03bc\u03b5\u03b8\u03bf\u03b4\u03bf\u03bb\u03bf\u03b3\u03af\u03b1 \u03c3\u03b5 \u03b1\u03c1\u03ba\u03b5\u03c4\u03ad\u03c2 \u03b1\u03c0\u03cc \u03b1\u03c5\u03c4\u03ad\u03c2 \u03c4\u03b9\u03c2 \u03b5\u03c1\u03b3\u03b1\u03c3\u03af\u03b5\u03c2 \u03b4\u03b5\u03bd \u03ae\u03c4\u03b1\u03bd \u03be\u03b5\u03ba\u03ac\u03b8\u03b1\u03c1\u03b7 \u03ba\u03b1\u03b9 \u03cc\u03c4\u03b9 \u03cc\u03bb\u03b5\u03c2 \u03b1\u03c6\u03bf\u03c1\u03bf\u03cd\u03c3\u03b1\u03bd \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03b1\u03c0\u03cc \u03c0\u03b5\u03c1\u03b9\u03bf\u03c7\u03ad\u03c2 \u03bc\u03b5 \u03c7\u03b1\u03bc\u03b7\u03bb\u03ac \u2013 \u03bc\u03ad\u03c4\u03c1\u03b9\u03b1 \u03b5\u03c0\u03af\u03c0\u03b5\u03b4\u03b1 Se. \u0395\u03c0\u03b9\u03c0\u03bb\u03ad\u03bf\u03bd, \u03c3\u03b5 \u03c0\u03bf\u03bb\u03bb\u03ad\u03c2 \u03b1\u03c0\u03cc \u03b1\u03c5\u03c4\u03ad\u03c2 \u03c4\u03b9\u03c2 \u03b5\u03c1\u03b3\u03b1\u03c3\u03af\u03b5\u03c2 \u03b4\u03b5\u03bd \u03c5\u03c0\u03ac\u03c1\u03c7\u03bf\u03c5\u03bd \u03bc\u03b5\u03c4\u03c1\u03ae\u03c3\u03b5\u03b9\u03c2 \u03b9\u03c9\u03b4\u03af\u03bf\u03c5 \u03b5\u03af\u03c4\u03b5 \u03c3\u03c4\u03bf \u03b1\u03af\u03bc\u03b1 \u03b5\u03af\u03c4\u03b5 \u03c3\u03c4\u03b1 \u03bf\u03cd\u03c1\u03b1. \u0395\u03c0\u03af\u03c3\u03b7\u03c2, \u03b4\u03b5\u03bd \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b5\u03be\u03b7\u03b3\u03b7\u03b8\u03b5\u03af \u03b5\u03cd\u03ba\u03bf\u03bb\u03b1 \u03b7 \u03b5\u03c5\u03b5\u03c1\u03b3\u03b5\u03c4\u03b9\u03ba\u03ae \u03b4\u03c1\u03ac\u03c3\u03b7 \u03c7\u03bf\u03c1\u03ae\u03b3\u03b7\u03c3\u03b7\u03c2 Se \u03bc\u03b5 \u03b2\u03ac\u03c3\u03b7 \u03c4\u03b1 \u03b5\u03c0\u03af\u03c0\u03b5\u03b4\u03b1 Se, \u03c4\u03b1 \u03b2\u03b1\u03c3\u03b9\u03ba\u03ac \u03b5\u03c0\u03af\u03c0\u03b5\u03b4\u03b1 TPO \u03b1\u03bd\u03c4\u03b9\u03c3\u03c9\u03bc\u03ac\u03c4\u03c9\u03bd, \u03c4\u03bf \u03c3\u03c4\u03ac\u03b4\u03b9\u03bf \u03c4\u03b7\u03c2 \u03bd\u03cc\u03c3\u03bf\u03c5 \u03ba\u03b1\u03b9 \u03c4\u03ad\u03bb\u03bf\u03c2 \u03b1\u03c0\u03cc \u03c4\u03bf \u03b5\u03af\u03b4\u03bf\u03c2 \u03ba\u03b1\u03b9 \u03c4\u03b7 \u03b4\u03cc\u03c3\u03b7 \u03c4\u03bf\u03c5 Se \u03c0\u03bf\u03c5 \u03c7\u03bf\u03c1\u03b7\u03b3\u03ae\u03b8\u03b7\u03ba\u03b5 (7-17).
\n\u03a0\u03c1\u03cc\u03c3\u03c6\u03b1\u03c4\u03b1 \u03b4\u03b9\u03b1\u03c0\u03b9\u03c3\u03c4\u03ce\u03b8\u03b7\u03ba\u03b5 \u03cc\u03c4\u03b9 \u03b7 \u03c7\u03bf\u03c1\u03ae\u03b3\u03b7\u03c3\u03b7 Se \u03c3\u03b5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03c0\u03bf\u03c5 \u03c0\u03ac\u03c3\u03c7\u03bf\u03c5\u03bd \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03bd\u03cc\u03c3\u03bf \u03c4\u03bf\u03c5 Graves (NG) \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b5\u03bb\u03b1\u03c4\u03c4\u03ce\u03c3\u03b5\u03b9 \u03c4\u03b1 \u03b1\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1 \u03c4\u03c9\u03bd \u03c5\u03c0\u03bf\u03b4\u03bf\u03c7\u03ad\u03c9\u03bd \u03c4\u03b7\u03c2 TSH (TRAbs) (18). \u039f \u03bc\u03b7\u03c7\u03b1\u03bd\u03b9\u03c3\u03bc\u03cc\u03c2 \u03b4\u03c1\u03ac\u03c3\u03b7\u03c2 \u03b1\u03c5\u03c4\u03ae\u03c2 \u03c4\u03b7\u03c2 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1\u03c2, \u03cc\u03c0\u03c9\u03c2 \u03b5\u03c0\u03af\u03c3\u03b7\u03c2 \u03c4\u03bf \u03b5\u03c5\u03b5\u03c1\u03b3\u03b5\u03c4\u03b9\u03ba\u03cc \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1 \u03c4\u03b7\u03c2 \u03c7\u03bf\u03c1\u03ae\u03b3\u03b7\u03c3\u03b7\u03c2 Se \u03c3\u03c4\u03b7\u03bd \u03c0\u03c1\u03cc\u03bb\u03b7\u03c8\u03b7 \u03c4\u03bf\u03c5 \u03ba\u03b1\u03c1\u03ba\u03af\u03bd\u03bf\u03c5 \u03c4\u03bf\u03c5 \u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03ae \u03b4\u03b5\u03bd \u03ad\u03c7\u03b5\u03b9 \u03bc\u03ad\u03c7\u03c1\u03b9 \u03c3\u03ae\u03bc\u03b5\u03c1\u03b1 \u03b4\u03b9\u03b5\u03c5\u03ba\u03c1\u03b9\u03bd\u03b9\u03c3\u03c4\u03b5\u03af (19).
\n\u03a4\u03b5\u03bb\u03b5\u03c5\u03c4\u03b1\u03af\u03b1 \u03b4\u03b9\u03b1\u03c0\u03b9\u03c3\u03c4\u03ce\u03b8\u03b7\u03ba\u03b5 \u03cc\u03c4\u03b9 \u03b7 \u03c7\u03bf\u03c1\u03ae\u03b3\u03b7\u03c3\u03b7 Se \u03ad\u03c7\u03b5\u03b9 \u03b5\u03c5\u03b5\u03c1\u03b3\u03b5\u03c4\u03b9\u03ba\u03ac \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1 \u03c3\u03b5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 \u03ae\u03c0\u03b9\u03b1 \u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03b9\u03ba\u03ae \u03bf\u03c6\u03b8\u03b1\u03bb\u03bc\u03bf\u03c0\u03ac\u03b8\u03b5\u03b9\u03b1 (\u0398\u039f). \u03a3\u03c5\u03b3\u03ba\u03b5\u03ba\u03c1\u03b9\u03bc\u03ad\u03bd\u03b1, \u03c3\u03b5 \u03c4\u03c1\u03b5\u03b9\u03c2 \u03bf\u03bc\u03ac\u03b4\u03b5\u03c2 \u03b1\u03c3\u03b8\u03b5\u03bd\u03ce\u03bd \u03c0\u03bf\u03c5 \u03ad\u03c0\u03b1\u03c3\u03c7\u03b1\u03bd \u03b1\u03c0\u03cc \u03ae\u03c0\u03b9\u03b1 \u0398\u039f \u03c7\u03bf\u03c1\u03b7\u03b3\u03ae\u03b8\u03b7\u03ba\u03b1\u03bd Se, placebo \u03ba\u03b1\u03b9 \u03c0\u03b5\u03bd\u03c4\u03bf\u03be\u03c5\u03c6\u03c5\u03bb\u03bb\u03af\u03bd\u03b7 \u03b3\u03b9\u03b1 6 \u03bc\u03ae\u03bd\u03b5\u03c2. \u0394\u03b9\u03b1\u03c0\u03b9\u03c3\u03c4\u03ce\u03b8\u03b7\u03ba\u03b5 \u03cc\u03c4\u03b9 \u03b7 \u03c7\u03bf\u03c1\u03ae\u03b3\u03b7\u03c3\u03b7 Se \u03b2\u03b5\u03bb\u03c4\u03af\u03c9\u03c3\u03b5 \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ac \u03c4\u03b1 \u03bf\u03c6\u03b8\u03b1\u03bb\u03bc\u03b9\u03ba\u03ac \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1, \u03cc\u03c0\u03c9\u03c2 \u03b5\u03c0\u03af\u03c3\u03b7\u03c2 \u03ba\u03b1\u03b9 \u03c4\u03b7\u03bd \u03c0\u03bf\u03b9\u03cc\u03c4\u03b7\u03c4\u03b1 \u03b6\u03c9\u03ae\u03c2 \u03b1\u03c5\u03c4\u03ce\u03bd \u03c4\u03c9\u03bd \u03b1\u03c3\u03b8\u03b5\u03bd\u03ce\u03bd. \u039f \u03bc\u03b7\u03c7\u03b1\u03bd\u03b9\u03c3\u03bc\u03cc\u03c2 \u03b4\u03c1\u03ac\u03c3\u03b7\u03c2 \u03ba\u03b1\u03b9 \u03b5\u03b4\u03ce \u03c0\u03b1\u03c1\u03b1\u03bc\u03ad\u03bd\u03b5\u03b9 \u03b5\u03bd \u03c0\u03bf\u03bb\u03bb\u03bf\u03af\u03c2 \u03ac\u03b3\u03bd\u03c9\u03c3\u03c4\u03bf\u03c2 (20).
\n\u0398\u03b1 \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03c3\u03b7\u03bc\u03b5\u03b9\u03c9\u03b8\u03b5\u03af \u03cc\u03c4\u03b9 \u03c3\u03c4\u03bf\u03c5\u03c2 \u03b1\u03c1\u03c1\u03ce\u03c3\u03c4\u03bf\u03c5\u03c2 \u03b1\u03c5\u03c4\u03bf\u03cd\u03c2 \u03b4\u03b5\u03bd \u03bc\u03b5\u03c4\u03c1\u03ae\u03b8\u03b7\u03ba\u03b1\u03bd \u03b5\u03c0\u03af\u03c0\u03b5\u03b4\u03b1 Se \u03c3\u03c4\u03bf \u03b1\u03af\u03bc\u03b1.
\n\u03a4\u03ad\u03bb\u03bf\u03c2, \u03c3\u03b5 \u03bc\u03af\u03b1 \u03c4\u03b5\u03bb\u03b5\u03c5\u03c4\u03b1\u03af\u03b1 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7 \u03c0\u03bf\u03c5 \u03b1\u03c6\u03bf\u03c1\u03ac \u03c4\u03bf \u03b8\u03ad\u03bc\u03b1 \u03b1\u03c5\u03c4\u03cc \u03ba\u03b1\u03b9 \u03b7 \u03bf\u03c0\u03bf\u03af\u03b1 \u03ad\u03b3\u03b9\u03bd\u03b5 \u03bc\u03b5 \u03c4\u03b7\u03bd \u03c0\u03c1\u03bf\u03c4\u03c1\u03bf\u03c0\u03ae \u03ba\u03b1\u03b9 \u03c4\u03b7\u03bd \u03bf\u03b9\u03ba\u03bf\u03bd\u03bf\u03bc\u03b9\u03ba\u03ae \u03b5\u03bd\u03af\u03c3\u03c7\u03c5\u03c3\u03b7 \u03c4\u03b7\u03c2 UEMS (European Union of Medical Specialties) \u03c4\u03bc\u03ae\u03bc\u03b1 \u0395\u03bd\u03b4\u03bf\u03ba\u03c1\u03b9\u03bd\u03bf\u03bb\u03bf\u03b3\u03af\u03b1\u03c2, \u0394\u03b9\u03b1\u03b2\u03ae\u03c4\u03b7 \u03ba\u03b1\u03b9 \u039c\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03b9\u03c3\u03bc\u03bf\u03cd, \u03ba\u03b1\u03b9 \u03c0\u03bf\u03c5 \u03b5\u03af\u03c7\u03b5 \u03c3\u03ba\u03bf\u03c0\u03cc \u03bd\u03b1 \u03c0\u03c1\u03bf\u03c3\u03b4\u03b9\u03bf\u03c1\u03b9\u03c3\u03c4\u03bf\u03cd\u03bd \u03c4\u03b1 \u03b5\u03c0\u03af\u03c0\u03b5\u03b4\u03b1 \u03c4\u03bf\u03c5 Se \u03c3\u03c4\u03bf \u03b1\u03af\u03bc\u03b1 \u03ba\u03b1\u03b9 \u03c4\u03bf\u03c5 \u03b9\u03c9\u03b4\u03af\u03bf\u03c5 \u03c3\u03c4\u03b1 \u03bf\u03cd\u03c1\u03b1 \u03c3\u03b5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 \u03b1\u03c5\u03c4\u03bf\u03ac\u03bd\u03bf\u03c3\u03b1 \u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03b9\u03ba\u03ac \u03bd\u03bf\u03c3\u03ae\u03bc\u03b1\u03c4\u03b1 (NH-NG) \u03c3\u03b5 \u03c3\u03c7\u03ad\u03c3\u03b7 \u03bc\u03b5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03c0\u03bf\u03c5 \u03ad\u03c0\u03b1\u03c3\u03c7\u03b1\u03bd \u03b1\u03c0\u03cc \u03bc\u03b7 \u03b1\u03c5\u03c4\u03bf\u03ac\u03bd\u03bf\u03c3\u03b1 \u03bd\u03bf\u03c3\u03ae\u03bc\u03b1\u03c4\u03b1 \u03c4\u03bf\u03c5 \u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03bf\u03cd\u03c2 \u03ba\u03b1\u03b9 \u03b1\u03c6\u03bf\u03c1\u03bf\u03cd\u03c3\u03b1\u03bd \u03b1\u03c1\u03c1\u03ce\u03c3\u03c4\u03bf\u03c5\u03c2 \u03b1\u03c0\u03cc 4 \u03b5\u03c5\u03c1\u03c9\u03c0\u03b1\u03ca\u03ba\u03ac \u03ba\u03c1\u03ac\u03c4\u03b7 \u03b4\u03b9\u03b1\u03c0\u03b9\u03c3\u03c4\u03ce\u03b8\u03b7\u03ba\u03b1\u03bd \u03c4\u03b1 \u03b5\u03be\u03ae\u03c2 \u03b5\u03bd\u03b4\u03b9\u03b1\u03c6\u03ad\u03c1\u03bf\u03bd\u03c4\u03b1:
\n\u039c\u03b5\u03bb\u03b5\u03c4\u03ae\u03b8\u03b7\u03ba\u03b1\u03bd 416 \u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03b9\u03ba\u03bf\u03af \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03ba\u03b1\u03b9 27 \u03bc\u03ac\u03c1\u03c4\u03c5\u03c1\u03b5\u03c2. \u03a3\u03c4\u03bf\u03c5\u03c2 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03ba\u03b1\u03b9 \u03bc\u03ac\u03c1\u03c4\u03c5\u03c1\u03b5\u03c2 \u03bc\u03b5\u03c4\u03c1\u03ae\u03b8\u03b7\u03ba\u03b1\u03bd \u03c4\u03b1 \u03b5\u03c0\u03af\u03c0\u03b5\u03b4\u03b1 Se \u03ba\u03b1\u03b9 \u03c3\u03b5\u03bb\u03b7\u03bd\u03bf\u03c0\u03c1\u03c9\u03c4\u03b5\u03ca\u03bd\u03b7\u03c2 P (SePP) \u03b1\u03af\u03bc\u03b1\u03c4\u03bf\u03c2 \u03cc\u03c0\u03c9\u03c2 \u03b5\u03c0\u03af\u03c3\u03b7\u03c2 \u03ba\u03c1\u03b5\u03b1\u03c4\u03b9\u03bd\u03af\u03bd\u03b7\u03c2 \u03ba\u03b1\u03b9 \u03b9\u03c9\u03b4\u03af\u03bf\u03c5 \u03c3\u03c4\u03b1 \u03bf\u03cd\u03c1\u03b1. \u039f\u03b9 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03c0\u03c1\u03bf\u03ae\u03c1\u03c7\u03bf\u03bd\u03c4\u03bf \u03b1\u03c0\u03cc 4 \u03ba\u03c1\u03ac\u03c4\u03b7 (\u0395\u03bb\u03bb\u03ac\u03b4\u03b1 \u2013 \u0398\u03b5\u03c3\u03c3\u03b1\u03bb\u03bf\u03bd\u03af\u03ba\u03b7 = 180 \u03ac\u03c1\u03c1\u03c9\u03c3\u03c4\u03bf\u03b9, \u03a1\u03bf\u03c5\u03bc\u03b1\u03bd\u03af\u03b1 \u2013 \u03a4\u03b9\u03bc\u03b9\u03c3\u03bf\u03ac\u03c1\u03b1 = 76, \u0391\u03c5\u03c3\u03c4\u03c1\u03af\u03b1 \u2013 \u0392\u03b9\u03ad\u03bd\u03bd\u03b7 = 83 \u03ba\u03b1\u03b9 \u03c4\u03ad\u03bb\u03bf\u03c2 \u0399\u03c4\u03b1\u03bb\u03af\u03b1 \u2013 \u03a1\u03ce\u03bc\u03b7 = 77 \u03ac\u03c1\u03c1\u03c9\u03c3\u03c4\u03bf\u03b9). \u0397 \u03b5\u03c1\u03b3\u03b1\u03c3\u03af\u03b1 \u03ae\u03c4\u03b1\u03bd \u03c0\u03c1\u03bf\u03bf\u03c0\u03c4\u03b9\u03ba\u03ae \u03ba\u03b1\u03b9 cross-sectional.
\n\u03a4\u03b1 \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03ad\u03c3\u03bc\u03b1\u03c4\u03b1 \u03ad\u03b4\u03b5\u03b9\u03be\u03b1\u03bd \u03bc\u03af\u03b1 \u03b3\u03c1\u03b1\u03bc\u03bc\u03b9\u03ba\u03ae \u03c3\u03c5\u03c3\u03c7\u03ad\u03c4\u03b9\u03c3\u03b7 \u03c4\u03bf\u03c5 Se \u03ba\u03b1\u03b9 \u03c4\u03b7\u03c2 SePP \u03c0\u03bf\u03c5 \u03ba\u03b1\u03c4\u03b1\u03b4\u03b5\u03b9\u03ba\u03bd\u03cd\u03b5\u03b9 \u03cc\u03c4\u03b9 \u03c4\u03bf\u03c5\u03bb\u03ac\u03c7\u03b9\u03c3\u03c4\u03bf\u03bd \u03c3\u03b5 \u03cc\u03c4\u03b9 \u03b1\u03c6\u03bf\u03c1\u03ac \u03b1\u03c5\u03c4\u03cc\u03bd \u03c4\u03bf\u03bd \u03c0\u03bb\u03b7\u03b8\u03c5\u03c3\u03bc\u03cc \u03b1\u03c3\u03b8\u03b5\u03bd\u03ce\u03bd \u03c4\u03b1 \u03b5\u03c0\u03af\u03c0\u03b5\u03b4\u03b1 Se \u03c3\u03c4\u03bf \u03c0\u03bb\u03ac\u03c3\u03bc\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03ba\u03b1\u03c4\u03ce\u03c4\u03b5\u03c1\u03b1 \u03c4\u03bf\u03c5 \u03c6\u03c5\u03c3\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03bf\u03cd. \u0391\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 \u03b1\u03c5\u03c4\u03bf\u03ac\u03bd\u03bf\u03c3\u03b1 \u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03b9\u03ba\u03ac \u03bd\u03bf\u03c3\u03ae\u03bc\u03b1\u03c4\u03b1 \u03b5\u03af\u03c7\u03b1\u03bd \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ac \u03c7\u03b1\u03bc\u03b7\u03bb\u03cc\u03c4\u03b5\u03c1\u03b1 \u03b5\u03c0\u03af\u03c0\u03b5\u03b4\u03b1 Se \u03ba\u03b1\u03b9 SePP \u03c3\u03b5 \u03c3\u03c7\u03ad\u03c3\u03b7 \u03bc\u03b5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 \u03bc\u03b7 \u03b1\u03c5\u03c4\u03bf\u03ac\u03bd\u03bf\u03c3\u03b1 \u03bd\u03bf\u03c3\u03ae\u03bc\u03b1\u03c4\u03b1. \u0397 \u0399\u03c4\u03b1\u03bb\u03af\u03b1 \u03b5\u03af\u03c7\u03b5 \u03c4\u03b1 \u03c5\u03c8\u03b7\u03bb\u03cc\u03c4\u03b5\u03c1\u03b1 \u03b5\u03c0\u03af\u03c0\u03b5\u03b4\u03b1 Se, SePP, \u03b9\u03c9\u03b4\u03af\u03bf\u03c5 \u03ba\u03b1\u03b9 \u03b9\u03c9\u03b4\u03af\u03bf\u03c5\/\u03ba\u03c1\u03b5\u03b1\u03c4\u03b9\u03bd\u03af\u03bd\u03b7\u03c2 \u03c3\u03c4\u03b1 \u03bf\u03cd\u03c1\u03b1 \u03c3\u03b5 \u03c3\u03c7\u03ad\u03c3\u03b7 \u03bc\u03b5 \u03cc\u03bb\u03b1 \u03c4\u03b1 \u03ac\u03bb\u03bb\u03b1 \u03b5\u03c5\u03c1\u03c9\u03c0\u03b1\u03ca\u03ba\u03ac \u03ba\u03c1\u03ac\u03c4\u03b7. \u03a4\u03b1 \u03b5\u03c0\u03af\u03c0\u03b5\u03b4\u03b1 Se \u03ba\u03b1\u03b9 SePP \u03c3\u03c7\u03b5\u03c4\u03af\u03b6\u03bf\u03bd\u03c4\u03b1\u03bd \u03b8\u03b5\u03c4\u03b9\u03ba\u03ac \u03bc\u03b5 \u03c4\u03b7\u03bd \u03b7\u03bb\u03b9\u03ba\u03af\u03b1, \u03b5\u03bd\u03ce \u03b4\u03b5\u03bd \u03b4\u03b9\u03b1\u03c0\u03b9\u03c3\u03c4\u03ce\u03b8\u03b7\u03ba\u03b5 \u03c3\u03c5\u03c3\u03c7\u03ad\u03c4\u03b9\u03c3\u03b7 Se \u03ba\u03b1\u03b9 \u03b9\u03c9\u03b4\u03af\u03bf\u03c5 \u03bf\u03cd\u03c1\u03c9\u03bd. \u03a4\u03ad\u03bb\u03bf\u03c2, \u03c4\u03b1 \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03ad\u03c3\u03bc\u03b1\u03c4\u03b1 \u03c0\u03bf\u03c5 \u03b1\u03c6\u03bf\u03c1\u03bf\u03cd\u03c3\u03b1\u03bd \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 \u0398\u039f \u03b4\u03b5\u03bd \u03bc\u03c0\u03bf\u03c1\u03bf\u03cd\u03bd \u03bd\u03b1 \u03b1\u03be\u03b9\u03bf\u03bb\u03bf\u03b3\u03b7\u03b8\u03bf\u03cd\u03bd \u03bb\u03cc\u03b3\u03c9 \u03c4\u03bf\u03c5 \u03cc\u03c4\u03b9 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03bb\u03bb\u03b7\u03bb\u03bf\u03c3\u03c5\u03b3\u03ba\u03c1\u03bf\u03c5\u03cc\u03bc\u03b5\u03bd\u03b1 \u03ba\u03b1\u03b9 \u03bf \u03b1\u03c1\u03b9\u03b8\u03bc\u03cc\u03c2 \u03c4\u03c9\u03bd \u03b1\u03c3\u03b8\u03b5\u03bd\u03ce\u03bd \u03bc\u03b9\u03ba\u03c1\u03cc\u03c2 (21).
\n\u03a4\u03bf \u03c3\u03c5\u03bc\u03c0\u03ad\u03c1\u03b1\u03c3\u03bc\u03b1 \u03b1\u03c5\u03c4\u03ae\u03c2 \u03c4\u03b7\u03c2 \u03c0\u03bf\u03bb\u03cd \u03b5\u03bd\u03b4\u03b9\u03b1\u03c6\u03ad\u03c1\u03bf\u03c5\u03c3\u03b1\u03c2 \u03b5\u03c1\u03b3\u03b1\u03c3\u03af\u03b1\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 \u03cc\u03c4\u03b9 \u03c4\u03b1 \u03c7\u03b1\u03bc\u03b7\u03bb\u03ac \u03b5\u03c0\u03af\u03c0\u03b5\u03b4\u03b1 Se \u03ba\u03b1\u03b9 SePP \u03c0\u03bf\u03c5 \u03b2\u03c1\u03ad\u03b8\u03b7\u03ba\u03b1\u03bd \u03c3\u03b5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 \u03b1\u03c5\u03c4\u03bf\u03ac\u03bd\u03bf\u03c3\u03b1 \u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03b9\u03ba\u03ac \u03bd\u03bf\u03c3\u03ae\u03bc\u03b1\u03c4\u03b1 \u03bc\u03c0\u03bf\u03c1\u03bf\u03cd\u03bd \u03bd\u03b1 \u03b5\u03be\u03b7\u03b3\u03ae\u03c3\u03bf\u03c5\u03bd \u03c4\u03b7\u03bd \u03b5\u03c5\u03b5\u03c1\u03b3\u03b5\u03c4\u03b9\u03ba\u03ae \u03b4\u03c1\u03ac\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03c7\u03bf\u03c1\u03ae\u03b3\u03b7\u03c3\u03b7\u03c2 Se \u03c3\u03b5 \u03b1\u03c5\u03c4\u03bf\u03cd\u03c2 \u03c4\u03bf\u03c5\u03c2 \u03b1\u03c1\u03c1\u03ce\u03c3\u03c4\u03bf\u03c5\u03c2.
\n\u0393\u03b5\u03bd\u03b9\u03ba\u03ac, \u03c4\u03bf \u03ba\u03b5\u03c6\u03ac\u03bb\u03b1\u03b9\u03bf \u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03ae\u03c2 \u03ba\u03b1\u03b9 \u03c3\u03b5\u03bb\u03ae\u03bd\u03b9\u03bf \u03c0\u03b1\u03c1\u03b1\u03bc\u03ad\u03bd\u03b5\u03b9 \u03b1\u03bd\u03bf\u03b9\u03ba\u03c4\u03cc \u03c3\u03b5 \u03ad\u03c1\u03b5\u03c5\u03bd\u03b1. \u03a0\u03bf\u03bb\u03bb\u03ad\u03c2 \u03ba\u03b1\u03b9 \u03ba\u03b1\u03bb\u03ac \u03c3\u03c7\u03b5\u03b4\u03b9\u03b1\u03c3\u03bc\u03ad\u03bd\u03b5\u03c2 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b5\u03c2 \u03b1\u03c0\u03b1\u03b9\u03c4\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9 \u03b1\u03ba\u03cc\u03bc\u03b1 \u03c0\u03c1\u03b9\u03bd \u03ba\u03b1\u03c4\u03b1\u03bb\u03ae\u03be\u03bf\u03c5\u03bc\u03b5 \u03c3\u03b5 \u03bf\u03c1\u03b9\u03c3\u03c4\u03b9\u03ba\u03ac \u03c3\u03c5\u03bc\u03c0\u03b5\u03c1\u03ac\u03c3\u03bc\u03b1\u03c4\u03b1.
\n\u0392\u03b9\u03b2\u03bb\u03b9\u03bf\u03b3\u03c1\u03b1\u03c6\u03af\u03b1<\/p>\n
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- Krassas GE, Pontikides N, Tziomalos K et al. Expert Rev Endocrinol Metab 2014.<\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"
\u03a4\u03bf 1817 \u03bf \u03a3\u03bf\u03c5\u03b7\u03b4\u03cc\u03c2 \u03c7\u03b7\u03bc\u03b9\u03ba\u03cc\u03c2 Berzelius \u03b1\u03bd\u03b1\u03ba\u03ac\u03bb\u03c5\u03c8\u03b5 \u03c4\u03bf \u03c3\u03c4\u03bf\u03b9\u03c7\u03b5\u03af\u03bf \u03c3\u03b5\u03bb\u03ae\u03bd\u03b9\u03bf (Se). \u03a4\u03bf \u03bf\u03bd\u03cc\u03bc\u03b1\u03c3\u03b5 \u03ad\u03c4\u03c3\u03b9 \u03b3\u03b9\u03b1 \u03bd\u03b1 \u03c4\u03b9\u03bc\u03ae\u03c3\u03b5\u03b9 \u03c4\u03b7\u03bd \u0398\u03b5\u03ac \u03c4\u03bf\u03c5 \u03c6\u03b5\u03b3\u03b3\u03b1\u03c1\u03b9\u03bf\u03cd \u03a3\u03b5\u03bb\u03ae\u03bd\u03b7 (1). 140 \u03c7\u03c1\u03cc\u03bd\u03b9\u03b1 \u03bc\u03b5\u03c4\u03ac \u03bf\u03b9 Schwarz \u03ba\u03b1\u03b9 Foltz \u03b1\u03bd\u03b1\u03ba\u03bf\u03af\u03bd\u03c9\u03c3\u03b1\u03bd \u03cc\u03c4\u03b9 \u03c4\u03bf Se \u03b5\u03af\u03bd\u03b1\u03b9 \u03bf\u03c5\u03c3\u03b9\u03ce\u03b4\u03b5\u03c2 \u03c3\u03c4\u03bf\u03b9\u03c7\u03b5\u03af\u03bf \u03b3\u03b9\u03b1 \u03c4\u03b7\u03bd \u03c5\u03b3\u03b5\u03af\u03b1 \u03c4\u03c9\u03bd \u03b6\u03ce\u03c9\u03bd, \u03cc\u03c4\u03b1\u03bd \u03b4\u03b9\u03b1\u03c0\u03af\u03c3\u03c4\u03c9\u03c3\u03b1\u03bd \u03cc\u03c4\u03b9 \u03af\u03c7\u03bd\u03b7 \u03b1\u03c0\u03cc \u03c4\u03bf \u03c3\u03c4\u03bf\u03b9\u03c7\u03b5\u03af\u03bf \u03b1\u03c5\u03c4\u03cc \u03c0\u03c1\u03bf\u03c3\u03c4\u03b1\u03c4\u03b5\u03cd\u03bf\u03c5\u03bd \u03c4\u03bf \u03ae\u03c0\u03b1\u03c1 \u03b1\u03c0\u03cc \u03bd\u03ad\u03ba\u03c1\u03c9\u03c3\u03b7 \u03c3\u03b5 \u03c0\u03bf\u03bd\u03c4\u03af\u03ba\u03b9\u03b1 \u03c0\u03bf\u03c5 \u03c0\u03ac\u03c3\u03c7\u03bf\u03c5\u03bd \u03b1\u03c0\u03cc \u03ad\u03bb\u03bb\u03b5\u03b9\u03c8\u03b7 \u03b2\u03b9\u03c4\u03b1\u03bc\u03af\u03bd\u03b7\u03c2 \u0395. \u039c\u03b5\u03c4\u03ac \u03b1\u03c0\u03cc \u03b1\u03c5\u03c4\u03ae \u03c4\u03b7\u03bd \u03b4\u03b9\u03b1\u03c0\u03af\u03c3\u03c4\u03c9\u03c3\u03b7 \u03ad\u03b3\u03b9\u03bd\u03b5 \u03b1\u03c0\u03bf\u03b4\u03b5\u03ba\u03c4\u03cc \u03cc\u03c4\u03b9 \u03c0\u03ac\u03c1\u03b1 \u03c0\u03bf\u03bb\u03bb\u03ad\u03c2 \u03b2\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ad\u03c2 \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b5\u03c2 \u03ad\u03c7\u03bf\u03c5\u03bd \u03ac\u03bc\u03b5\u03c3\u03b7 \u03c3\u03c7\u03ad\u03c3\u03b7 \u03bc\u03b5 \u03c4\u03bf Se (1,2). \u0398\u03b1 \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03c3\u03b7\u03bc\u03b5\u03b9\u03c9\u03b8\u03b5\u03af \u03cc\u03c4\u03b9 \u03c4\u03bf Se \u03c3\u03b5 \u03bc\u03b5\u03b3\u03ac\u03bb\u03b5\u03c2 \u03c0\u03b5\u03c1\u03b9\u03b5\u03ba\u03c4\u03b9\u03ba\u03cc\u03c4\u03b7\u03c4\u03b5\u03c2 \u03b3\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03c4\u03bf\u03be\u03b9\u03ba\u03cc \u03bc\u03b5 \u03b4\u03c5\u03c3\u03bc\u03b5\u03bd\u03b5\u03af\u03c2 \u03b5\u03c0\u03b9\u03b4\u03c1\u03ac\u03c3\u03b5\u03b9\u03c2 \u03c3\u03b5 \u03c0\u03bf\u03bb\u03bb\u03ad\u03c2 \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b5\u03c2 \u03c4\u03bf\u03c5 \u03bf\u03c1\u03b3\u03b1\u03bd\u03b9\u03c3\u03bc\u03bf\u03cd. <\/p>\n
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